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Compression of the neck of the sitting subject caused increase in urinary sodium output without change in glomerular filtration (creatinine clearance) or apparent cardiac output (electrokymograph). The possible existence of an intracranial mechanism sensitive to alterations in volume of extracellular fluid and regulating the volume of extracellular fluid is suggested.

The Effect of Posture and of Compression of the Neck on Excretion of Electrolytes and Glomerular Filtration: Furthur Studies