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TO THE various appellations that contemporary historians are attaching to the decade of the sixties, medicine could well add the title, the "Age of Therapeutic Plenty." The veritable flood of samples of new drugs, of descriptive literature, and of promotional gimcracks that crosses the desk of the practicing physician each day is ample testimony of the "drug explosion" of recent years. In cardiovascular disease, for example, the advent of anticoagulant therapy and the development of potent hypotensive and oral diuretic agents have provided many new preparations, while the dozens of coronary and peripheral vasodilators, of sedatives and tranquilizers and of products intended to lower blood cholesterol further contribute to this prolific growth. Hand i-n hand with the increased potential for pharmacological therapy in cardiac disease has gone the development of cardiovascular surgery, which began meekly with a few simple shunts and bypasses and now is rapidly approaching the realm of the fantastic, limited not by lack of daring or dexterity, or by instrumental deficiency, but by basic immunologic phenomena, which themselves are seemingly not immutable. As a result, not only does the lay press glow with therapeutic enthusiasm, but even the professional literature abounds with information of hopeful portent.

The Physician's Responsibility in the Age of Therapeutic Plenty