Serum Glutamic-Oxalacetic Transaminase in Coronary Artery Disease

The results of serial glutamic-oxalacetic transaminase (GOT) assays in 201 cases in which coronary artery disease was suspected are correlated with the clinical, laboratory, and electrocardiographic changes. In 95 per cent of the cases diagnosed as myocardial infarction on the basis of clinical and electrocardiographic evidence there was an elevation of serum GOT. On the other hand, in 12 per cent of the cases in which clinical and electrocardiographic findings were negative or equivocal with regard to myocardial infarction, there was an elevated serum GOT. In 18 cases that were autopsied the correlation between acute myocardial necrosis and serum GOT elevation was 100 per cent.