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Two patients with congestive cardiac failure were placed on a metabolic balance regimen and supplemental sodium chloride was administered. Weight changes in these patients could be closely correlated with the amount of sodium retention and appeared to be initially independent of brachial venous pressure thus supporting the concept that edema in congestive failure results from prinmary sodium retention rather than primary elevation in venous pressure.

The Relationship of Sodium Retention and Venous Pressures to Edema Formation