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Sodium and potassium levels of the contents of the terminal ileum and feces were determined for four dogs at different dietary sodium intakes, both before and during administration of a carboxylic cation-exchange resin. With restriction of dietary sodium, there was more sodium bound by the resin in the terminal ileum than was provided by the diet. There was considerable conservation of sodium in the upper gastrointestinal tract, but the colon always absorbed a major part of the sodium presented to it. During resin administration with very low sodium diets there was more sodium in the feces than in the diets.

Electrolyte Changes in Ileal Contents and in Feces during Restriction of Dietary Sodium with and without the Administration of Cation-Exchange Resin