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Gene therapy is a promising approach for the treatment of cardiac diseases. Coexpression of therapeutic genes with a suitable marker gene would allow for the noninvasive imaging of successful gene transfer and expression via radiolabeled marker substrates. In the present study, such an approach was first applied to cardiac tissue.

circulation

Uptake of Radiolabeled 2′-Fluoro-2′-Deoxy-5-Iodo-1-β- <scp>d</scp> -Arabinofuranosyluracil in Cardiac Cells After Adenoviral Transfer of the Herpesvirus Thymidine Kinase Gene

Uptake of Radiolabeled 2′-Fluoro-2′-Deoxy-5-Iodo-1-β- d -Arabinofuranosyluracil in Cardiac Cells After Adenoviral Transfer of the Herpesvirus Thymidine Kinase Gene