Classic Preconditioning Decreases the Harmful Accumulation of Nitric Oxide During Ischemia and Reperfusion in Rat Hearts
Author(s) -
Csaba Csonka,
Zoltán Szilvássy,
Ferenc Fülöp,
Tibor Páli,
Ingolf E. Blasig,
Árpád Tósaki,
Richard Schulz,
Péter Ferdinándy
Publication year - 1999
Publication title -
circulation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.795
H-Index - 607
eISSN - 1524-4539
pISSN - 0009-7322
DOI - 10.1161/01.cir.100.22.2260
Subject(s) - ischemia , medicine , ischemic preconditioning , nitric oxide , reperfusion injury , cardiology , cardiac function curve , anesthesia , nitric oxide synthase , pharmacology , heart failure
The role of NO in the mechanism of preconditioning is not understood. Therefore, we studied the effect of preconditioning and subsequent ischemia/reperfusion on myocardial NO content in the presence of an NO synthase (NOS) inhibitor.
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