Open AccessThe Rate of Disappearance of Lanatoside C. and Digitoxin from the Blood of Rats
Author(s) -
René Bine,
Meyer Friedman,
CATHERINE BLAND
Publication year - 1950
Publication title -
circulation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.795
H-Index - 607
eISSN - 1524-4539
pISSN - 0009-7322
DOI - 10.1161/01.cir.1.5.1182
Subject(s) - digitoxin , medicine , pharmacology , embryonic heart , heart rate , digitalis , digoxin , endocrinology , blood pressure , biochemistry , embryonic stem cell , heart failure , chemistry , gene
By means of the embryonic duck heart preparation, both lanatoside C. and digitoxin could be detected and quantitatively measured in the sera of rats after parenteral administration of both drugs. A study of the behavior of the two glycosides in blood indicated that a striking difference existed in the respective rates of disappearance of both drugs from the bloodstream.
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