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The current understanding of the pathophysiology of coronary artery disease is based largely on postmortem studies. Optical coherence tomography (OCT) is a high-resolution ( approximately 10 microm), catheter-based imaging modality capable of investigating detailed coronary plaque morphology in vivo.

In Vivo Characterization of Coronary Atherosclerotic Plaque by Use of Optical Coherence Tomography