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Preeclampsia is a serious disorder of pregnancy characterized by hypertension, proteinuria, edema, and coagulation and vascular abnormalities. At the cellular level, abnormalities include increased calcium concentration in platelets, lymphocytes, and erythrocytes. Recent studies have shown that antibodies directed against angiotensin II type I (AT1) receptors are also highly associated with preeclampsia.

Antibodies From Preeclamptic Patients Stimulate Increased Intracellular Ca 2+ Mobilization Through Angiotensin Receptor Activation

Antibodies From Preeclamptic Patients Stimulate Increased Intracellular Ca ²⁺ Mobilization Through Angiotensin Receptor Activation