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The chemokine fractalkine activates platelets and induces leukocyte adhesion to the endothelium. Expression of fractalkine and its receptor, CX3CR1, is elevated in coronary artery disease. We assessed the effects of fractalkine on vascular function in isolated rat aorta.

The CX 3 C Chemokine Fractalkine Induces Vascular Dysfunction by Generation of Superoxide Anions

The CX ₃ C Chemokine Fractalkine Induces Vascular Dysfunction by Generation of Superoxide Anions