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Emerging evidence suggests that human blood contains bone marrow (BM)-derived endothelial progenitor cells that contribute to postnatal neovascularization. Clinical trials demonstrated that administration of BM-cells can enhance neovascularization. Most studies, however, used crude cell populations. Identifying the role of different cell populations is important for developing improved cellular therapies.

arteriosclerosis, thrombosis, and vascular biology

CD34 <sup>+</sup> Cells Home, Proliferate, and Participate in Capillary Formation, and in Combination With CD34 <sup>−</sup> Cells Enhance Tube Formation in a 3-Dimensional Matrix

CD34 + Cells Home, Proliferate, and Participate in Capillary Formation, and in Combination With CD34 − Cells Enhance Tube Formation in a 3-Dimensional Matrix

CD34 ⁺ Cells Home, Proliferate, and Participate in Capillary Formation, and in Combination With CD34 ⁻ Cells Enhance Tube Formation in a 3-Dimensional Matrix