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Fas ligand (FasL) can induce apoptosis in cells bearing the Fas receptor. The role of FasL in the vasculature with regard to atherosclerosis is controversial. This study examined the function of endothelial FasL during atherosclerosis.

Endothelial Overexpression of Fas Ligand Decreases Atherosclerosis in Apolipoprotein E–Deficient Mice