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Trying to understand osseointegration, many researches look for better means to evaluate this healing process. In order to analysis this healing process around NAPIO implants is rabbits tibia, a double follow-up was done (torque removal forces and histology). Seven animals were used in this study and each one received 2 implants (one for confocal scanning laser microscopy analysis and the other to obtain the removal torque). The animals received 3 bone labelers injections of Tetracicline, Alizarine and Calceine on different intervals. Day 0 14 implants on 7 animals Day 7 Tetracicline on 6 animals (1, 2, 3, 4, 5 and 6) Day 15 Sacrifice animals 1 and 2, and Alizarine animais 3, 4, 5 and 6 Day 21 Alizarine on animals 3, 4, 5 and 6 Day 45 Sacrifice animals 3 and 4; Calceine animals 5 and 6 Day 52 Calceine on animais 5 and 6 Day 90 Sacrifice animals 5 and 6 Day 180 Sacrifice animals 7 (no bone labeler)

Estudo Metodológico de Avaliação do Crescimento Ósseo ao Redor de Implantes Osseointegrados Através de Microscopia Confocal de Varredura a Laser e Torque de Remoção.