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GUIMARÃES, M. A. B. V. Non invasive monitoring of suppression of the ovarian cyclic activity and estrus behavior of female African Lions (Panthera leo), induced by the use of implants of GnRH analog, deslorelin. [Monitoração nãoinvasiva da supressão da atividade ovariana cíclica e do comportamento de estro em fêmeas de leão africano (Panthera leo), induzidos pelo uso de implantes de análogo de GnRH, deslorelina]. 2008. 78 f. Tese (Livre-Docência) – Faculdade de Medicina Veterinária e Zootecnia, Universidade de São Paulo, São Paulo, 2008. The objective of this study was to evaluate the efficiency of the use of application of subcutaneous implants of a GnRH analog, Deslorelin, for the suppression of the ovarian cycle activity and estrus behavior, in 5 adult female African Lions (Panthera leo). The endocrine monitoring was performed by the extraction and measurement of fecal metabolites of sexual steroids, progesterone and estradiol. It was also observed the occurance of typical estrus behavior (heat). The effect of the implant overcame the expectations, abolishing the heat behavior for 22, 31 and 33 months for three of the females. The forth lioness, has not yet shown heat behavior and has already been implanted for 35 months. The fifth lioness was euthanized for reasons unrelated to this study. In the same manner, the non invasive monitoring was shown to be effective and precise, demonstrating the abolishment of ovarian activity during the whole period of the experiment. During the period studied, there was an remarkable decrease of aggressiveness between the lionesses, with a consequent overall improvement. Although the reversibility of the ovarian function has not been demonstrated during the experimental period, the results obtained suggest that it should re-establish soon. This information is of great relevance for the applying of the method for population control programs and for the reduction of aggressiveness in lions and potentially in other wild felids.

Monitoração não-invasiva da supressão da atividade ovariana cíclica e do comportamento de estro em fêmeas de leão africano (Panthera leo), induzidos pelo uso de implantes de análogo de GnRH, deslorelina.