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Williams-Beuren syndrome (WBS) is a rare genetic disorder characterized by peculiar facies, eyes, dental, cardiovascular, renal, and skeletal abnormalities, mental retardation, friendly and loquacious personality, and occasionally hypercalcemia in infancy. The orofacial aspects and especially the dental management of these patients have received little attention in the literature. The aim of this manuscript is to describe four cases of patients with WBS attended at Special Care Dentistry Center, School of Dentistry, University of Sao Paulo, with emphasis on the oral findings and systemic conditions of dental interest. The clinical management of patients with WBS is discussed. We conclude that congenital heart defects and behavioral changes are the aspects that most interfere on dental treatment

Medical considerations in the dental treatment of patients with Williams-Beuren syndrome - report of four clinical cases