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Ciccone FH. Vigilância de sindrome febril exantematica: estudo descritivo de casos com anticorpos da classe IgM contra o sarampo. Estado de Sao Paulo, 2000 a 2004./Febrile exanthematic syndrome surveillance: descriptive study of cases with antibody of IgM class anti-measles. State of Sao Paulo, 2000 to 2004 [dissertation]. Sao Paulo (BR): Faculdade de Saude Publica da Universidade de Sao Paulo; 2007. Objective: To describe cases of febrile exanthematic syndrome reported in the State of Sao Paulo between 2000 and 2004, in order to identify possible measles residual source of infection. Methods: A descriptive study, using the same definitions of Measles Elimination Plan. The study included reported cases of febrile exanthematic syndrome surveillance with antibody of IgM class by ELISA and/or capture ELISA techniques. The clinical and epidemiological characteristics were described in terms of time, space and personal characteristics. Results: 463 possible cases of measles were analyzed: 64.1% and 29.8% were classified, respectively, as exposed and unexposed to vaccine; 15.3% presented specific measles clinical and 12.1% presented clinical complications. The age groups most represented were: 9 to 11 months (36.5%), one year (32.8%) and five years old or over (15.2%). The temporal and spatial distribution did not suggest the presence of a chain of transmission of febrile exanthematic disease. Between the end of 2000 and the beginning of 2002, high levels of cases unexposed to vaccine were maintained, which coincided with the identification of two imported cases of measles. Conclusion: The limitations of the study did not allow conclusive analyses regarding the circulation of the measles virus in the State, but the study points towards the need to carry out exhaustive investigations on possible residual sources of infection among: infants under nine months old, first vaccinated against measles before the age of 10 months, women of fertile age and cases unexposed to anti-measles vaccine. Descriptors: measles, febrile exanthematic syndrome, surveillance, elimination.

Vigilância de síndrome febril exantemática: estudo descritivo de casos com anticorpos da classe IgM contra o sarampo, Estado de São Paulo, 2000 a 2004