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Approximately 40% of the non-Hodgkin's Lymphomas occuroutside lymph node tissue and thus are denominated extranodallymphoma. In the gastrointestinal tract, the stomach is thecommonest location involved with the presentation of MALT anddiffuse large B-cell lymphomas (DLBCL). In Brazil, despite theirimportance and frequency there are very few epidemiological dataconcerning lymphomas, especially those of extranodal origin. Inorder to study the features of primary gastric lymphomas in aBrazilian population, 60 patients were retrospectively evaluated.Thirty-eight cases (63.3%) were classified as DLBCL and 22 (36.6%)as MALT lymphoma. There were no significant differences betweenthe 2 groups in terms of gender, age, gastric symptoms, "B"symptoms, bulky disease, bone marrow infiltration, stage, H. pyloriinfection and laboratory and endoscopic findings. Differenttreatment methods were adopted. The complete remission rate was73.1% for DLBCL and 95% for MALT lymphoma. The diseasefree survival at 7 years was 84.8 for DLBCL and 94.1% for MALTlymphoma. The 7 year overall survival rate for DLBCL was 65.7%and 5 year overall survival for MALT was 92.9%. As we could notdemonstrate differences between the two histological types, weconclude that a correct histological diagnosis is essential for choosingthe best therapeutic approach.

revista brasileira de hematologia e hemoterapia

Linfoma não Hodgkin extralinfonodal gástrico: estudo retrospectivo do Serviço de Hematologia do Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo