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Free-Knot Spline Regression for Modeling Multiphase Growth Curve In this work, we present the free-knot spline regression models as an alternative to the nonlinear models used in multiphase growth curves. We will study the blind search algorithm through the gold section to choose the best number of knot and their respective locations. The package freeknotspline of the free software R was used to fit the proposed models. The Akaike information criterion was used to choose the best model for different degrees of the polynomial associated with the spline. Simulation studies were performed to better understand the position of the knot, location and degree of the polynomial related to spline regression models of free-knots, and how this may affect the goodness of fit of the model. Based on our simulation study, we propose an empirical way of determining the number of knots, letting the search algorithm choose the position of the knots. The methodology is applied to the multiphase growth data of Hereford breed females.

Regressão spline de nós livres para modelagem de curvas de crescimento multifásica