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Infection due to multidrug-resistant microorganisms is a growing threat in healthcare settings.  Acinetobacter  species specifically  A. baumannii  is increasingly becoming resistant to most antimicrobial agents recommended for treatment. This study aimed to determine the antimicrobial susceptibility pattern of  Acinetobacter  species isolated from patients in Kenyatta National Hospital.    Methods  We conducted a retrospective study based on VITEK 2 (BioMérieux) electronic records capturing identification and antimicrobial susceptibility of  Acinetobacter  isolates from patient samples analyzed between 2013 and 2015 at Kenyatta National Hospital microbiology laboratory. Generated data were analyzed using WHONET and SPSS.    Results  A total of 590  Acinetobacter  isolates were analyzed. 85% of the isolates tested were multi-drug resistant (MDR). Among the 590 isolates, 273 (46%) were from tracheal aspirates and 285 (48%) from the critical care unit.  A. baumannii  was the most frequently isolated species with high susceptibility to amikacin (77%) and poor susceptibility to ciprofloxacin (69-76%), tobramycin (37%) and meropenem (27%). Both  A. lwoffii  and  A. haemolyticus  had high susceptibility to amikacin (80-100%) and meropenem (75-100%).    Conclusion   A. baumannii  is resistant to commonly administered antibiotics. There is need for continuous antimicrobial resistance surveillance especially in health care facilities and strengthening of antibiotic stewardship programmes which will contribute to enhancement of infection control policies.

Antimicrobial susceptibility pattern of acinetobacter isolates from patients in Kenyatta National Hospital, Nairobi, Kenya