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Alveolar development and lung parenchymal simplification are not well characterized in vivo in neonatal patients with respiratory morbidities, such as bronchopulmonary dysplasia (BPD). Hyperpolarized (HP) gas diffusion magnetic resonance imaging (MRI) is a sensitive, safe, nonionizing, and noninvasive biomarker for measuring airspace size in vivo but has not yet been implemented in young infants.

neonatology

Alveolar Airspace Size in Healthy and Diseased Infant Lungs Measured via Hyperpolarized &lt;sup&gt;3&lt;/sup&gt;He Gas Diffusion Magnetic Resonance Imaging