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Primary ciliary dyskinesia (PCD) is a rare genetic disease leading to recurrent respiratory infections of upper and lower airways. Chronic rhinosinusitis (CRS) and bronchiectasis are very common in PCD patients. Recently, it has been shown the presence of taste receptors in respiratory tract and the possible involvement of bitter taste receptor TAS2R38 gene in susceptibility to respiratory infections and rhinosinusitis.

international archives of allergy and immunology

Primary Ciliary Dyskinesia: The Impact of Taste Receptor (&lt;b&gt;&lt;i&gt;TAS2R38&lt;/i&gt;&lt;/b&gt;) Gene Polymorphisms on Disease Outcome and Severity