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Objective:   To highlight the usefulness of apixaban on intra-atrial thrombus that develops after previous treatment with warfarin.   Clinical Presentation and Intervention:   A 69-year-old woman with a history of atrial fibrillation treated with warfarin presented with acute decompensated heart failure due to an episode of atrial fibrillation. Transesophageal echocardiogram revealed the presence of an intra-atrial thrombus. She was treated with apixaban, and transesophageal echocardiogram showed complete resolution of the thrombus after 3 weeks of treatment.   Conclusion:   This case highlights the usefulness of apixaban in the management of atrial fibrillation and proven intra-atrial thrombus.

Thrombolytic Action of Apixaban on Intra-Atrial Thrombus Developed after Previous Treatment with Warfarin: A Case Report