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Background: The aim of the present study was to assess the incremental value of Speckle Tracking\udEchocardiography (STE) for differentiation between CP and RCM. Although normal or\udexaggerated early diastolic mitral annular velocity provides high specificity for differentiating\udconstrictive pericarditis (CP) from restrictive cardiomyopathy (RCM), its sensitivity has been\udshown to be lower.\udMethods: Twelve patients with CP, 8 with RCM, and 12 healthy controls were studied. Standard\udmitral inflow Doppler and tissue Doppler echocardiography (TDI) were performed. LV TDI\udannular peak systolic and diastolic velocities (S’, E’) and time difference between onset of mitral\udinflow (E velocity) and onset of E' (E'-E time) were measured. LV longitudinal strain and systolic\udand diastolic strain rate were obtained in the basal, mid and apical segments of septal and lateral\udwalls in apical 4-chamber view both by STE. Circumferential and radial strain and averaged LV\udrotation and rotational velocities from the base and apex were also obtained by STE.\udResults: E' and S' were significantly higher in patients with CP than RCM (9.1 ± 1.4 vs 4.4 ±\ud1.6cm/s, and 7.8 ± 1.2 vs 4.2 ± 1.4cm/s respectively, p <0.001). E'-E was significantly shorter in\udpatients with CP (25.8 ± 21.6 vs 56.5 ± 24.4ms, p <0.005). Impairment of longitudinal strain in\udthe antero-lateral wall (ALWLS) was shown in CP patients compared to controls (-14.2 ± 2.9 vs -\ud20.1 ± 2.8%, p<0.001) whereas circumferential and radial strain values did not change\udsignificantly. ROC curves suggested that the thresholds offering an adequate compromise between\udsensitivity and specificity for detection of CP were -15.2% for ALWLS (AUC 0.87), 32.8 ms for\udE’-E time (AUC 0.78), and -5.1 cm/sec for E’ velocity (AUC 0.72).\udConclusions: STE indices provide incremental diagnostic information to conventional Doppler\udechocardiography and can be helpful to differentiate between CP and RCM

cardiology

International Academy of Cardiology Annual Scientific Sessions 2015. 20th World Congress on Heart Disease Vancouver, B.C., Canada, July 25-27, 2015: Abstracts