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Reflectance confocal microscopy (RCM) is a noninvasive technique for in vivo imaging of the skin that allows evaluation of the total lesion area. This case report about a 66-year-old patient with a clinically indistinctive, previously treated erythematous lesion on the frontal part of the face demonstrates the use of RCM to select the proper biopsy location.

In vivo Reflectance Confocal Microscopy: A Useful Tool to Select the Location of a Punch Biopsy in a Large, Clinically Indistinctive Lesion