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Diagnosis and immunotherapy of house-dust mite (HDM) allergy is still based on natural allergen extracts. The aim of this study was to analyze commercially available Dermatophagoides pteronyssinus extracts from different manufacturers regarding allergen composition and content and whether variations may affect their allergenic activity.

international archives of allergy and immunology

Varying Allergen Composition and Content Affects the in vivo Allergenic Activity of Commercial &lt;b&gt;&lt;i&gt;Dermatophagoides pteronyssinus&lt;/i&gt;&lt;/b&gt; Extracts