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Prohepcidin and the active form hepcidin-25 are two variants of the peptide hormone hepcidin for iron homoeostasis. Their regulatory role and usefulness as biomarkers of the iron status are uncertain. Our aim is to describe the intra-individual variance of serum and urinary hepcidin-25 and prohepcidin concentrations, the mutual associations of the 4 hepcidin formats, and their correspondence with iron status variables in male Guatemalan volunteers.

annals of nutrition and metabolism

Reproducibility of and Correspondence among Different Hepcidin Forms in Blood and Urine and Their Relationships to Iron Status in Healthy, Male Guatemalan Volunteers Observed over 9 Weeks