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Christofredo (also Christfried or Christian) Jakob is considered the father of neurology, neurobiology and forensic histopathology in Argentina, where he initially worked between 1899-1910 and then from 1913 onwards. He held professorships of neurobiology at the Faculty of Humanities and Educational Sciences of the University of La Plata and of anatomy and biology at the University of Buenos Aires, and established one of the most important neuropathological laboratories in South America. In the latter phase of his career, Jakob published important works on the pathological anatomy of neurological and neuropsychiatric disorders and formalized ideas on consciousness and neurophilosophy.

Semicentennial Tribute to the Ingenious Neurobiologist Christfried Jakob (1866–1956). 2. Publications from the Second Argentina Period, 1913–1949