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Previous studies in vitro and in animals in vivo found that alpha-linolenic acid (C18:3omega3) may enhance oxidative damage of essential amino acids. We investigated whether the addition of the long-chain polyunsaturated fatty acids (LCPUFA) arachidonate (C20:4omega-6; AA) and docosahexaenoate (C22:6-omega3; DHA) in the form of egg phospholipids to infant formula affects plasma amino acid concentrations and indices of protein metabolism in term infants.

annals of nutrition and metabolism

Effects of Dietary Long-Chain Polyunsaturated Fatty Acids on Plasma Amino Acids and Indices of Protein Metabolism in Infants: Results from a Randomized Clinical Trial