Open AccessForecast: Rough Seas for Leukemia
Author(s) -
David M. Hockenbery
Publication year - 2014
Publication title -
cancer discovery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.795
H-Index - 163
eISSN - 2159-8290
pISSN - 2159-8274
DOI - 10.1158/2159-8290.cd-14-0084
Subject(s) - leukemia , profiling (computer programming) , computational biology , chronic myelogenous leukemia , cancer , cancer research , gene expression profiling , biology , bioinformatics , gene , computer science , genetics , gene expression , programming language
Expression of BCL-2, BCL-XL, and MCL-1 in acute myelogenous leukemia is highly variable. Cellular BH3 profiling can help decide which are likely to respond to BCL-2-targeted BH3 mimetics.
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