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Appreciation of the immune effects of targeted agents has grown, and efforts to combine these agents with immunotherapy are underway to enhance therapeutic responses. Multiple ongoing trials are examining this concept; however, nuances exist with regard to timing, sequence, and combinatorial strategies. Clin Cancer Res; 23(2); 327-9. ©2016 AACRSee related article by Deniger et al., p. 351.

Gene Targeting Meets Cell-Based Therapy: Raising the Tail, or Merely a Whimper?