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Exposure to higher levels of melatonin may be associated with lower breast cancer risk, but epidemiologic evidence has been limited. We examined the relationship in a case-control study nested within the Diagnostisch Onderzoek Mammacarcinoom (DOM) study and conducted a meta-analysis of prospective studies.

Urinary Melatonin in Relation to Breast Cancer Risk: Nested Case–Control Analysis in the DOM Study and Meta-analysis of Prospective Studies