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Persistent infection with oncogenic human papillomavirus (HPV) types-16 and -18 is an established cause of cervical and other cancers. Some studies report detection of oncogenic HPV DNA in colorectal carcinomas, with prevalence estimates as high as 84%. However, other studies report detecting no HPV DNA in colorectal tumors.

cancer epidemiology, biomarkers and prevention

Human Papillomavirus DNA Is Rarely Detected in Colorectal Carcinomas and Not Associated with Microsatellite Instability: The Seattle Colon Cancer Family Registry