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Oncogenic human papillomaviruses (HPV) are sexually transmitted and linked to several epithelial malignancies, but an association between HPV and colorectal neoplasia is not established. Previously, we reported a three-fold increase in the odds of colorectal hyperplastic polyps associated with oncogenic HPV seropositivity in men but detected no HPV DNA in colorectal tissues from these same men.

cancer epidemiology, biomarkers and prevention

No Association between Antibodies to Sexually Transmitted Infections and Colorectal Hyperplastic Polyps in Men: Minnesota Cancer Prevention Research Unit Polyp Study