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Multiple chromosome 8q24 genotypic variants are strongly implicated in several cancers. Recent genome-wide association studies of urinary bladder cancer report risk to be associated with the T allele of rs9642880 on 8q24 among individuals of European descent.

cancer epidemiology, biomarkers and prevention

Risk of Urinary Bladder Cancer Is Associated with 8q24 Variant rs9642880[T] in Multiple Racial/Ethnic Groups: Results from the Los Angeles–Shanghai Case–Control Study