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We undertook a case-control study in an Australian Caucasian population-based sample of 1,246 cases and 664 controls to assess the roles of detoxification gene polymorphisms EPHX T&gt;C Tyr(113)His, GSTT1 deletion, GSTM1 deletion, and GSTP1 A&gt;G Ile(105)Val on risk of breast cancer.

cancer epidemiology, biomarkers and prevention

A Systematic Approach to Analysing Gene-Gene Interactions: Polymorphisms at the Microsomal Epoxide Hydrolase EPHX and Glutathione S-transferase GSTM1, GSTT1, and GSTP1 Loci and Breast Cancer Risk