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Hospital acquired infection due to Serratia marcescens, a ubiquitous saprophyte, is significantly increasing1•`3, 16, 19). A majority of such S. marcescens strains are highly resistant, and in fact, the emergence of multiple drug resistant strains of genus Serratia is more prevalent than any other commonly occurring members of the family Enterobacteriaceae of clinical origin12). The presence of transferable R plasmids with resistance markers to ampicillin (ABPC), chloramphenicol (CP), gentamicin

Drug resistance and R plasmid in clinical isolates of Serratia marcescens at Shinshu University Hospital.