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Objective. To investigate the changes in vertebral function after minimally invasive surgery in patients with thoracolumbar spinal fractures and investigate the impact of percutaneous minimally invasive surgery on patients’ quality of life by following up the patients in the long term. Methods. A retrospective analysis was performed to select 80 patients with thoracolumbar spinal fractures treated in our hospital from April 2013 to October 2018, and the patients were divided into a study group and a control group according to the difference in their choice of procedure. The two groups were compared in terms of perioperative wound pain, serum creatine kinase (CK) activity, and C-reactive protein (CRP) levels, and the two groups were followed up for 2 years to compare the changes in anterior vertebral body height and Cobb’s angle during the follow-up period and to compare the differences in quality of life between the two groups. Results. (1) The pain level of patients in the study group was significantly lower than that of the control group at the 1st and 3rd postoperative days ( p &lt; 0.05 ). (2) The CK activity and CPR level of patients in the study group were significantly lower than that of the control group at the 1st and 3rd postoperative days ( p &lt; 0.05 ). (3) Compared with the preoperative period, the height of the anterior border of the vertebral body and the Cobb’s angle in both groups showed significant changes at 7 d, 6 months, one year, and two years after surgery ( p &lt; 0.05 ), suggesting that both procedures can significantly restore the height of the injured vertebra and improve the function of the vertebral body. (4) The somatic, physical, and psychological functions of patients in the study group were significantly greater than those in the control group at 6 months postoperatively ( p &gt; 0.05 ). Conclusion. Compared to traditional open surgery, minimally invasive percutaneous surgery for thoracolumbar fractures can significantly reduce perioperative pain and improve perioperative stress in patients, while achieving better surgical outcomes and a significantly improved quality of life in patients at long-term follow-up.

computational and mathematical methods in medicine

Evaluation of Vertebral Function and Long-Term Quality of Life after Percutaneous Minimally Invasive Surgery in Patients with Thoracolumbar Spine Fractures