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Slice-to-volume reconstruction (SVR) method can deal well with motion artifacts and provide high-quality 3D image data for fetal brain MRI. However, the problem of sparse sampling is not well addressed in the SVR method. In this paper, we mainly focus on the sparse volume reconstruction of fetal brain MRI from multiple stacks corrupted with motion artifacts. Based on the SVR framework, our approach includes the slice-to-volume 2D/3D registration, the point spread function- (PSF-) based volume update, and the adaptive kernel regression-based volume update. The adaptive kernel regression can deal well with the sparse sampling data and enhance the detailed preservation by capturing the local structure through covariance matrix. Experimental results performed on clinical data show that kernel regression results in statistical improvement of image quality for sparse sampling data with the parameter setting of the structure sensitivity 0.4, the steering kernel size of 7 × 7 × 7 and steering smoothing bandwidth of 0.5. The computational performance of the proposed GPU-based method can be over 90 times faster than that on CPU.

A Sparse Volume Reconstruction Method for Fetal Brain MRI Using Adaptive Kernel Regression