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Background   Epilepsy is a disease of the brain defined by any of the following conditions. First, at least two unprovoked (or reflex) seizures occurring greater than 24 hours apart, and secondly, the presence of one unprovoked (or reflex) seizure and a probability of further seizures. Due to persisted misunderstandings and negative attitudes, individuals living with epilepsy live with a poor quality of life. Therefore, this study aimed to assess the community general knowledge about epilepsy and attitude towards person living with epilepsy and its associated factors.Methods   A community-based cross-sectional study conducted from March 10 to June 10, 2019, to assess the community general knowledge and attitude towards epilepsy and its associated factors. Data were entered into Epi data version 3.1 and transported to SPSS version 21 for analysis.Results   596 study participants participated in a response rate of 98%. Among the study participants, 43.6% (95% CI: 39.6, 47.5) had poor knowledge and 41.3% (95% CI: 37.4, 45.1) had an unfavorable attitude. Lack of modern education, married, never witnessed a seizure, and not hearing the term epilepsy showed statistically significant association with poor knowledge about epilepsy. Lack of modern education, earning less than 1000 Ethiopian birr, not witnessing seizure, not hearing the term epilepsy, and half to one-hour walking time from health facility variables showed statistically significant association with the unfavorable attitude about epilepsy.Conclusions   The current study revealed that nearly half of Debre Berhan dwellers have deficits in terms of general knowledge about epilepsy and attitude towards a person living with epilepsy. Poor knowledge about epilepsy and unfavorable attitude towards a person living with epilepsy are likely to have an important impact on stigmatization and treatment-seeking behavior, and it should be given due attention. It would be better if health educators give special emphasis for the individuals with predictors of poor knowledge and unfavorable attitude.

Public Knowledge and Attitude towards Epilepsy and Its Associated Factors: Community-Based Cross-Sectional Study, Ethiopia, 2019