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The total phenolic and flavonoid contents (TPC and TFC) from the genus  Hosta  with antioxidant and  α -glucosidase inhibitory activities were reported for the first time. Sixteen extracts from the aboveground and underground parts of the four  Hosta  species, including  H. plantaginea ,  H. ventricosa ,  H. ensata , and  H. albofarinosa , using reflux extraction (RE) and ultrasound-assisted extraction (UAE) techniques have high TPC and TFC with good antioxidant and  α -glucosidase inhibitory activities. Furthermore, no significant differences on extraction yields, TPC, and TFC were found between RE and UAE techniques. Additionally, extracts from the aboveground parts of the four  Hosta  species had higher TPC, TFC, antioxidant, and  α -glucosidase inhibitory activities compared to the underground parts by means of RE or UAE techniques. Lastly, the extracts of  H. albo-marginata  displayed a very remarkable  α -glucosidase inhibitory activity compared to the positive control acarbose. The relationships of sixteen extracts of the four  Hosta  species were analyzed by RE and UAE techniques between extraction yields, TPC, TFC, antioxidant activity, and  α -glucosidase inhibitory activity. The present study demonstrated that  H. plantaginea ,  H. ventricosa ,  H. ensata , and  H. albofarinosa  could be new sources of natural antioxidants and antidiabetes for pharmaceutical and industrial purposes.

biomed research international

Extraction of Phenolics and Flavonoids from Four Hosta Species Using Reflux and Ultrasound-Assisted Methods with Antioxidant and α-Glucosidase Inhibitory Activities