English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

The aim of this study was to explore the epidemiology of  Toxoplasma gondii  infection in patients with colorectal cancer (CRC) in eastern China. Therefore, 287 primary CRC patients and 287 age-matched healthy control subjects were recruited to estimate the seroprevalence of  T. gondii  and identify the risk factors of infection. Enzyme-linked immunoassays were used to test for anti- T. gondii  immunoglobulin G (IgG) and IgM antibodies. Forty-six (16%) samples were positive for anti- T. gondii  IgG antibodies in patients with CRC, compared with 26 (9.1%) in the healthy controls, a significant difference ( P  = 0.007). By contrast, eight (2.8%) patients tested positive for  T. gondii  IgM antibodies, compared with three (1.1%) in the controls, a difference that was not significant ( P  = 0.13). Multivariable backward stepwise logistic regression analysis revealed that a rural residence (OR 2.83; 95% CI 1.15–7.01;  P  = 0.024) and treatment with chemotherapy (OR 2.16; 95% CI 1.02–4.57;  P  = 0.045) were risk factors for  T. gondii  infection in patients with CRC. Thus,  T. gondii  infection is serious in patients with CRC, and a rural residence and treatment with chemotherapy are independent risk factors for infection by this parasite. Therefore, medical professionals should be aware of this pathogen in patients with CRC, and the causes of  T. gondii  infection in these patients need to be explored further.

biomed research international

Increased Risk of Toxoplasma gondii Infection in Patients with Colorectal Cancer in Eastern China: Seroprevalence, Risk Factors, and a Case–Control Study