English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

Background and Aims   Exercise activity is an important method for managing type 2 diabetes. This investigation examined the HIIT and continuous training on  apelin ,  APJ receptor ,  NO , and  cardiotrophin-1  in the cardiac tissue of diabetic rats.Methods   The animals were categorized into 3 groups of HIIT, continuous (CO), and control (C) (all animals were sacrificed immediately and 2 days after exercise training period). Rats underwent the treadmill exercise program either HIIT (12 bouts at 90–95% of VO 2  max with 60 s rest at 50% of VO 2  max) or CO (60–65% VO 2  max for 40 min). Protocols performed 5 days per week for 8 weeks. Apelin, APJ receptor, NO, and cardiotrophin-1 protein expressions were measured using the Western blotting method in the left ventricle.Results   Immediately after HIIT and CO exercise protocols,  apelin  and  CT-1  protein showed a significant difference in contrast by the C-0 group ( p  < 0.01). However,  NO  values were substantially higher in HIIT-0 compared to C-0 and CO-0 groups rats ( p  < 0.01). After two days of exercise protocols,  apelin  and  NO  protein showed a significant increase in HIIT and CO groups in contrast to the C animals ( p  < 0.01). Moreover,  APJ  and  CT-1  protein significantly upregulated in CO-2 and HIIT-2 compared to the other groups ( p  < 0.01).Conclusions   This study indicates that exercise training, despite the type, is an efficient method to modify  apelin ,  APJ receptor ,  NO , and  cardiotrophin-1  values in animals with type 2 diabetes.

Comparing High-Intensity Interval Training (HIIT) and Continuous Training on Apelin, APJ, NO, and Cardiotrophin-1 in Cardiac Tissue of Diabetic Rats