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Objectives   To develop and formulate a new experimental dentifrice with and without fluoride based on the peel and the fruit of the  Passiflora mollissima  (tumbo) and also to evaluate its antimicrobial activity against seven bacterial strains.Methods   The sample was calculated using the mean comparison formula, obtaining wells ( n  = 12) for each of the strains evaluated:  S. mutans ,  E. faecalis ,  Actinomyces ,  Lactobacillus ,  C. albicans ,  S. sanguinis , and  S. oralis . The antibacterial activity of the dentifrice was evaluated by the direct contact technique.Results   It was found that the highest antimicrobial activity was only present in pulp-based dentifrices against strains of  S. mutans  21.0 ± 1.8,  E. faecalis  16.3 ± 3.9,  Actinomyces  22.1 ± 1.3, and  Lactobacillus  21.0 ± 1.3. However, in comparison with other strains such as  C. albicans ,  S. sanguinis , and  S. oralis , the peel-based dendrifrice of  Passiflora mollissima  obtained the highest antimicrobial activity.Conclusion   The experimental dentifrice based on  Passiflora mollissima  had an antibacterial effect against the seven microbial strains during the first 24 and 48 hours.

international journal of dentistry

Development and Formulation of the Experimental Dentifrice Based on<i>Passiflora mollissima</i>(Tumbo) with and without Fluoride Anion: Antibacterial Activity on Seven Antimicrobial Strains

Development and Formulation of the Experimental Dentifrice Based onPassiflora mollissima(Tumbo) with and without Fluoride Anion: Antibacterial Activity on Seven Antimicrobial Strains