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Background   We report a case of multiple keratocysts first diagnosed in an 8-year-old boy.Case report   The incidental radiographic finding of a cystic lesion in an 8-year-old boy led to the surgical enucleation and further diagnosis of a keratocyst associated with a tooth crown. In the course of dental maturation from deciduous to permanent teeth, the boy presented new lesions, always associated with the crowns of teeth. Gorlin-Goltz (nevoid basal-cell carcinoma) syndrome was suspected, and the genetic analysis detected a previously undescribed germline variant in the  PTCH1  gene.Treatment   This included a surgical removal of the cystic lesions, as well as the affected teeth.Follow-up   Due to the high recurrence rate of the keratocysts, frequent radiological checks were performed over a 5-year period.

case reports in dentistry/case reports in dentistry

Multiple, Multiloculated, and Recurrent Keratocysts of the Mandible and Maxilla in Association with Gorlin-Goltz (Nevoid Basal-Cell Carcinoma) Syndrome: A Pediatric Case Report and Follow-up over 5 Years