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Visualization provides an interactive investigation of details of interest and improves understanding the implicit information. There is a strong need today for the acquisition of high quality visualization result for various fields, such as biomedical or other scientific field. Quality of biomedical volume data is often impacted by partial effect, noisy, and bias seriously due to the CT (Computed Tomography) or MRI (Magnetic Resonance Imaging) devices, which may give rise to an extremely difficult task of specifying transfer function and thus generate poor visualized image. In this paper, firstly a nonlinear neural network based denoising in the preprocessing stage is provided to improve the quality of 3D volume data. Based on the improved data, a novel region space with depth based 2D histogram construction method is then proposed to identify boundaries between materials, which is helpful for designing the proper semiautomated transfer function. Finally, the volume rendering pipeline with ray-casting algorithm is implemented to visualize several biomedical datasets. The noise in the volume data is suppressed effectively and the boundary between materials can be differentiated clearly by the transfer function designed via the modified 2D histogram.

Region Space Guided Transfer Function Design for Nonlinear Neural Network Augmented Image Visualization