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Early diagnosis and appropriate treatment for carbapenem-resistant  Klebsiella pneumoniae  (CR- Kp ) infection is a big challenge for clinicians due to its high mortality. Every effort has been made to improve its clinical outcomes. However, treatment according to synergy susceptibility testing has never been reported in the literature. We reported a 29-year-old systemic lupus erythematosus female with CR- Kp  blood stream infection. We highlighted the identification by next generation sequencing and treatment according to synergy susceptibility testing in the case.

case reports in infectious diseases

Use of Next Generation Sequencing and Synergy Susceptibility Testing in Diagnosis and Treatment of Carbapenem-Resistant Klebsiella pneumoniae Blood Stream Infection