English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

Cancer is one of the most occurring diseases in developed and developing countries. Plant-based compounds are still researched for their anticancer activity and for their quantity in plants. Therefore, the modern chromatographic methods are applied to quantify them in plants, for example, UPLC-MS/MS (ultraperformance liquid chromatography tandem mass spectrometry). Therefore, the aim of the present study was to evaluate the content of sanguinarine, berberine, protopine, and chelidonine in  Dicentra spectabilis  (L.) Lem.,  Fumaria officinalis  L.,  Glaucium flavum  Crantz,  Corydalis cava  L.,  Berberis thunbergii  DC.,  Meconopsis cambrica  (L.) Vig.,  Mahonia aquifolium  (Pursh) Nutt.,  Macleaya cordata  Willd., and  Chelidonium majus  L. For the first time, N,N-dimethyl-hernovine was identified in  M. cambrica ,  B. thunbergii ,  M. aquifolium ,  C. cava ,  G. flavum , and  C. majus ; methyl-hernovine was identified in  G. flavum ; columbamine was identified in  B. thunbergii ; and methyl-corypalmine, chelidonine, and sanguinarine were identified in  F. officinalis  L. The richest source of protopine among all the examined species was  M. cordata  (5463.64 ± 26.3  μ g/g). The highest amounts of chelidonine and sanguinarine were found in  C. majus  (51,040.0 ± 1.8  μ g/g and 7925.8 ± 3.3  μ g/g, resp.), while  B. thunbergi  contained the highest amount of berberine (6358.4 ± 4.2  μ g/g).

UPLC-MS/MS Profile of Alkaloids with Cytotoxic Properties of Selected Medicinal Plants of the Berberidaceae and Papaveraceae Families