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Background   We investigated the integron types and their relation with antibiotic resistance among  A. baumannii  isolates collected from intensive care unit patients, Babol, north of Iran.Methods   In this cross-sectional study, a total of 73 bronchoalveolar lavage samples were obtained from patients in ICU. Susceptibility testing was performed by disk diffusion method. Types of integrons were identified by an integrase gene PCR.Results   In total, 47.9%  A. baumannii  isolates were recovered from the BAL samples. All isolates were resistant to ceftazidime. 91.4% and 58.3% of isolates were MDR and XDR, respectively. The rate of colistin resistance with the  E -test was 5.7%. Molecular analysis of class I, II, and III integrons showed that 25.7%, 88.6%, and 28.6% of the isolates carried the  intI ,  intII , and  intIII  genes, respectively.Discussion   Our results show that different classes of integrons are commonly spread among  A. baumannii  strains and these genomic segments can play an important role in the acquisition of MDR and XDR phenotypes. So monitoring drug resistance in  A. baumannii  isolates with the use of  int  gene PCR is very important to plan specific infection control measures to prevent the spread of MDR-AB and XDR-AB in Iran's hospitals.

Integron-Mediated Antibiotic Resistance inAcinetobacter baumanniiIsolated from Intensive Care Unit Patients, Babol, North of Iran