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This study aimed to investigate the effects of electroacupuncture at the Lieque, Chize, and Zusanli points in patients with lung injury caused by severe acute pancreatitis. Patients with acute respiratory distress syndrome (ARDS) induced by severe acute pancreatitis (SAP) were randomly divided into three groups based on the treatment: conventional therapy alone (group A), electroacupuncture of nonacupoints with conventional therapy (group B), and electroacupuncture at the Lieque (LU7), Chize (LU5), and Zusanli (ST36) points (group C) once a day for 5 days. Arterial blood samples were obtained for blood gas analysis before electroacupuncture ( T 1) and 3 ( T 2) and 5 ( T 3) days after electroacupuncture. The oxygenation index was significantly higher in all groups at  T 2 and  T 3 than that at  T 1, while the APACHE-II scores were decreased significantly. The expression of TNF- α  was significantly decreased and the IL-10 was significantly increased in all groups at  T 3. The oxygenation index at  T 2 and  T 3 was significantly higher in group C than that in group B. Electroacupuncture at Lieque, Chize, and Zusanli can lessen the lung injury induced by SAP, and the mechanism may be related to the decreased TNF- α  and increased IL-10 value. Clinical Registration Number is  ChiCTR-ICR-15006850 .

Clinical Effect of Electroacupuncture on Lung Injury Patients Caused by Severe Acute Pancreatitis